Endocrine Abstracts

Introduction: Mucinous ovarian cystoadenoma with stromal luteinization and hilar cell hyperplasia is a rare cause of hirsutism and virilization and only few cases are described in literature. We present a rare case of mucinous cystadenoma with hypertestosteronemia.A 38-years old woman came to our observation for severe hirsutism and oligomenorrhea. Hormonal work-up showed severe hypertestosteronemia (total testosterone: 4.39 ng/ml) with high levels of DH...

Cushing’s disease, i.e. cortisol excess due to an ACTH-secreting pituitary adenoma, is a rare disorder with considerable morbidity and mortality. Current therapeutic strategies include pituitary surgery, radiation, adrenalectomy and medical treatment with steroidogenesis inhibitors, as drugs aimed at the pituitary adenoma are as yet under investigation. Experimental data showed that retinoic acid restrains ACTH secretion by tumoral corticotrophes thus we decided to evalua...

Introduction: Metoclopramide is known to exert stimulatory effects on catecholamine secretion, having been used in the past as provocative test in the diagnosis of pheochromocytoma. We describe a patient with an incidentally discovered pheochromocytoma after metoclopramide administration.Case report: A 64 years-old woman underwent total thyroidectomy for multinodular goiter with ‘follicular proliferation Thy 3’ at FNAB of the target nodule. The...

Aim: To develop a cost-effective instrument to evaluate the preoperative malignancy risk of thyroid nodules (TNs).Patients&Methods: A meta-analysis of the clinical (C) and ultrasonographic (U) features associated with an increased risk of malignancy was conducted searching in the PubMed database. For each of them we computed the odds ratio and we consequently assigned a score. The resulted C+U score along with the 5-tiered score of fine-needle aspira...